https://cai-lab.net/home daily 1.0 2023-08-15 https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1592163241496-6EEAK7R0GHIM0UVFFVZW/YAP+phase+separation+image+copy.png Home Master transcription co-activator YAP (in green) forms biomolecular condensates in cell under hyperosmotic stress, and attracts transcription factor (TEAD1, in magenta) into the droplets. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1627495369528-4H2MR3OSDMPZ4EZFEPIK/IMG_5659+2.jpeg Home - Make it stand out Celebration for the R35 MIRA grant-2021 https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/039ff664-b670-493d-a7ed-b707f621a702/IMG_5323.jpg Home - Make it stand out Cai Lab attending the BMB Departmental Retreat-Fall 2022 https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/2d5c8592-1100-4082-b81b-5dc271dae940/NIGMS+logo.jpg Home - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/8b98888c-0175-479f-a935-42640278c9ac/CDMRP+Logo.jpeg Home - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/ff2bbf50-2c23-4754-975f-f66d3b3e3095/Bloomberg.logo.small.horizontal.blue.png Home - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://cai-lab.net/research daily 0.75 2025-07-02 https://cai-lab.net/our-team2/danfengcai daily 0.75 2022-06-10 https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/dc74bcb6-46c7-40e7-9c74-53d483504335/HART2349.jpg DanfengCai Danfeng Cai, Ph.D. https://cai-lab.net/publications daily 0.75 2025-07-02 https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/2b482bf1-4650-4818-adba-e1ee06214f7a/Graphic+abstract_TFE3+fusion.jpg Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/690c8094-7c5a-4c14-bfe4-7d7a8ad41b73/Graphical+abstract+for+YAP+iScience+paper.jpeg Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/86702bb2-c0de-4faf-8a85-a00182fca901/Phase+separation+in+the+nucleus.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/bc397a08-0b3c-445a-8e87-e1a3bd8d6a4c/Figure+1_Nucleus_20230516.jpeg Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/e68e57d9-2002-472d-b2c5-61ae05daf4fe/102122_Figures.jpg Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/78e1e9a3-b259-406f-ae2f-801b144363e9/Therapeutic+Potential.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1616184324178-5ZDA1I84A74QCLWTG1HD/1-s2.0-S0968000421000049-gr2.jpg Publications https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1591847389014-A5P5RRLKQJL7OYSSQBUP/YAP+phase+separation+image+copy.png Publications - Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression. Cai, D., D. Feliciano, P. Dong, E. Flores, M. Gruebele, N. Porat-Shliom, S. Sukenik, Z. Liu and J. Lippincott-Schwartz Nature Cell Biology, 2019 https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1591850141286-5Z2HVON27CX7PM46HLTD/PNAS+paper+graph.jpg Publications https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1591850735303-ZO0WSANI69TZAP51DESA/Screen+Shot+2020-06-11+at+12.29.25+AM.png Publications https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1591851430169-F2HH21I0I5X2JUX46HBA/source+and+sink+image.jpg Publications https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1591852125927-IV6HL257J45Y3C1A7C9C/nihms759549f1.jpg Publications https://cai-lab.net/join-us daily 0.75 2023-09-07 https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1592768938792-VWPYLASYHH9CWHANYLB7/maxresdefault.jpg Join Us - Join us! We are always looking for highly motivated students and fellows to join us. Postdoctoral candidate, please submit your cover letter and CV to Dr. Cai. Graduate students (PhD and MHS, ScM) currently in the BMB Program of JHSPH, BCMB program of JHMI, and CMM Program of JHMI should contact Dr. Cai for a lab rotation. Email: danfeng.cai {at} jhu.edu https://cai-lab.net/new-page daily 0.75 2025-07-02 https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/adb0b24d-8640-43bf-970b-5383e84adbcd/Kajiken+lab+2024.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/62519e02-e987-4b14-b17f-21f418400efe/lab+ice+skating+2024.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/7d444c0b-e004-461b-933f-28d20045954a/2023+Cai+lab+holiday.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/abf72d0e-caa5-48a4-9ded-ed18f383a83b/IMG_6824.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/67ee4ece-3f28-42c1-8612-ddb9df0e891e/IMG_6831.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/cfdffd32-e32b-4df8-892f-203d6570ce6b/IMG_5748.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/c74ca150-6c21-47bd-baa9-353ec1cf72e4/Lab+photo_2022+holiday.jpg Lab News - Make it stand out Secret Santa-Dec 2022 https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/039ff664-b670-493d-a7ed-b707f621a702/IMG_5323.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/49a08796-c88d-4581-a1cb-d0286883d2cc/IMG_3834+2.JPG Lab News - Make it stand out Siyuan Hao https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/9bc52742-719c-46cc-9c68-29cb6b241f52/Choon+poster.jpg Lab News - Make it stand out Choon Leng So, PhD https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/eed8f262-4850-44dd-83ac-6aff9854c6be/IMG_3951+copy.jpg Lab News - Make it stand out Justin Demmerle, PhD https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/38dc4e71-e574-4c59-b5fb-c8498707401b/IMG_3869+2+copy.jpg Lab News - Make it stand out Jane Lee https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/fbd9e5f6-ee63-460a-9528-74e9691ac138/Cai+Lab+Icerink.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/53ffa1bd-0306-4db3-a8a2-0d8a46ba7e93/Image.jpeg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/a0534eab-836f-406a-8864-9b4689772978/Jane+Lee.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/bfdbddb9-1439-43d6-8278-c3dcc2ebd630/IMG_0005.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1631734948654-X723KTTL506IFXUZYFTB/cmm_logo.png Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1627495019213-AHMYQRZUS6RXC81B4UA7/IMG_5647.jpeg Lab News - Make it stand out Image credit: Britney He https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1627495145016-9347T1FX6IQ8SU8OLQ7R/IMG_5659+2.jpeg Lab News - Make it stand out Image credit: ?? https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1627495089070-CF76F6DVGPV5K6PAB2E0/IMG_5658.jpeg Lab News - Make it stand out Image credit: Britney He https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1625885596599-CHMDYAPVSY1OMEG2AN69/Cai+Lab+photo+2.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1621531366835-9515VLIAW12ADVSWL155/Demmerle_headshot_2016.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1618600287392-8KF3Z0T0IN05121N56PF/IMG_8246.jpg Lab News https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1618600317669-WR40N5BZ4ZQ2HVK98X2S/IMG_8247.jpg Lab News https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1606245010499-FPQD4F3H7I0ANE0E4PJ3/image-asset.jpeg Lab News Future open lab space https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1606245308547-HXPGLJG928TKLO8FWT0T/IMG_7159.jpg Lab News Future hallway https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1606245431192-DUCEKH6XM3XGMAGR25FU/IMG_7162.jpg Lab News Future meeting room with great city view https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1598632541595-O9AQJBG4GRCYPC680V9B/IDPSeminars.jpg Lab News https://cai-lab.net/our-team2 daily 0.75 2026-03-23 https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/dc74bcb6-46c7-40e7-9c74-53d483504335/HART2349.jpg https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/40ce3857-591d-4f5d-aad0-bc0b04ba3eef/Choon+Leng+So+photo.JPG https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/bf2ed578-03b7-4109-bdc0-6c279505f841/SongtaoYe.jpg https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/7bc861e8-a49c-48ce-a401-01b05eb5925f/Jane+Lee.jpg https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/8806f38e-f281-4458-bf1b-4cdcc565b9d7/Ethan+Black+Hopkins+Picture.jpg https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/aa1a267c-15f9-4192-b6e2-2b19f46bc32e/Yiran+Wang.JPG https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/d002f8e8-6810-4248-ab87-7bb7b36c644a/Gesztesi-Juliana.jpeg https://cai-lab.net/justin-demmerle daily 0.75 2021-06-26 https://images.squarespace-cdn.com/content/v1/5ec53934e211ef2d6b3dcb2a/1621529911836-XX09LR5FBR2F8I5ZVPYU/Demmerle_headshot_2016.jpg Justin Demmerle Justin Demmerle, Ph.D.